This panel will describe the findings from various survey and poll data sources regarding the public’s trust and perceptions in the media and government as credible sources of health information, how these perceptions have changed over time, and how trust in government impacts willingness to comply with government health recommendations. Particular focus will be placed on how the public perceives CDC in this regard. Source results will be discussed in terms of principles for developing effective health messages, and lessons learned to help practitioners disseminate information through appropriate channels to public audiences.